A Combination of Sulindac and Antimicrobial Eradication of H. pylori Prevents Progression of Gastric Cancer in Hypergastrinemic INS-GAS Mice

Helicobacter pylori infection causes severe dysplasia manifested as gastrointestinal intraepithelial neoplasia (GIN) after 28 weeks post H. pylori infection (WPI) in cancer-prone, hypergastrinemic male INS-GAS mice. We examined the efficacy of the NSAID sulindac (400 ppm in drinking water) alone, th...

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Main Authors: Lee, Chung-Wei, Rickman, Barry, Rogers, Arlin B., Muthupalani, Sureshkumar, Takaishi, Shigeo, Yang, Peiying, Wang, Timothy C., Fox, James G.
Format: Artigo
Jezik:Inglês
Izdano: 2009
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766772/
https://ncbi.nlm.nih.gov/pubmed/19826057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-3856
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