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A randomized, double-blind, placebo-controlled trial of simvastatin to treat Alzheimer disease
BACKGROUND: Lowering cholesterol is associated with reduced CNS amyloid deposition and increased dietary cholesterol increases amyloid accumulation in animal studies. Epidemiologic data suggest that use of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) may decrease th...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Lippincott Williams & Wilkins
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3149154/ https://ncbi.nlm.nih.gov/pubmed/21795660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e318228bf11 |
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