Impact on Disease Development, Genomic Location and Biological Function of Copy Number Alterations in Non-Small Cell Lung Cancer

Lung cancer, of which more than 80% is non-small cell, is the leading cause of cancer-related death in the United States. Copy number alterations (CNAs) in lung cancer have been shown to be positionally clustered in certain genomic regions. However, it remains unclear whether genes with copy number...

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Hlavní autoři: Huang, Yen-Tsung, Lin, Xihong, Chirieac, Lucian R., McGovern, Ray, Wain, John C., Heist, Rebecca S., Skaug, Vidar, Zienolddiny, Shanbeh, Haugen, Aage, Su, Li, Christiani, David C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149069/
https://ncbi.nlm.nih.gov/pubmed/21829676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022961
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