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A Double-Layered Mixture Model for the Joint Analysis of DNA Copy Number and Gene Expression Data
Copy number aberration is a common form of genomic instability in cancer. Gene expression is closely tied to cytogenetic events by the central dogma of molecular biology, and serves as a mediator of copy number changes in disease phenotypes. Accordingly, it is of interest to develop proper statistic...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Mary Ann Liebert, Inc.
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3148827/ https://ncbi.nlm.nih.gov/pubmed/20170400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2009.0019 |
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