Phenobarbital but Not Diazepam Reduces AMPA/kainate Receptor Mediated Currents and Exerts Opposite Actions on Initial Seizures in the Neonatal Rat Hippocampus

Diazepam (DZP) and phenobarbital (PB) are extensively used as first and second line drugs to treat acute seizures in neonates and their actions are thought to be mediated by increasing the actions of GABAergic signals. Yet, their efficacy is variable with occasional failure or even aggravation of re...

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Detalles Bibliográficos
Main Authors: Nardou, Romain, Yamamoto, Sumii, Bhar, Asma, Burnashev, Nail, Ben-Ari, Yehezkel, Khalilov, Ilgam
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Research Foundation 2011
Assuntos:
Neuroscience
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148783/
https://ncbi.nlm.nih.gov/pubmed/21847371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2011.00016
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