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Anti-tumor activity of liposome encapsulated fluoroorotic acid as a single agent and in combination with liposome irinotecan

To test the hypothesis that co-delivery of synergistic drug combinations in the same liposome provides a better anti-tumor effect than the drugs administered in separate liposomes, fluoroorotic acid (FOA) alone and in combination with irinotecan (IRN) were encapsulated in liposomes and evaluated for...

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Autors principals: Riviere, Kareen, Jerger, Katherine, Szoka, Francis C.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148779/
https://ncbi.nlm.nih.gov/pubmed/21600250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2011.05.005
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