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Matrix Gla protein deficiency causes arteriovenous malformations in mice

Arteriovenous malformations (AVMs) in organs, such as the lungs, intestine, and brain, are characteristic of hereditary hemorrhagic telangiectasia (HHT), a disease caused by mutations in activin-like kinase receptor 1 (ALK1), which is an essential receptor in angiogenesis, or endoglin. Matrix Gla pr...

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Detalhes bibliográficos
Main Authors: Yao, Yucheng, Jumabay, Medet, Wang, Anthony, Boström, Kristina I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148746/
https://ncbi.nlm.nih.gov/pubmed/21765215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI57567
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