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Matrix Gla protein deficiency causes arteriovenous malformations in mice
Arteriovenous malformations (AVMs) in organs, such as the lungs, intestine, and brain, are characteristic of hereditary hemorrhagic telangiectasia (HHT), a disease caused by mutations in activin-like kinase receptor 1 (ALK1), which is an essential receptor in angiogenesis, or endoglin. Matrix Gla pr...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Clinical Investigation
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3148746/ https://ncbi.nlm.nih.gov/pubmed/21765215 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI57567 |
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