CGRP induction in cystic fibrosis airways alters the submucosal gland progenitor cell niche in mice

In cystic fibrosis (CF), a lack of functional CF transmembrane conductance regulator (CFTR) chloride channels causes defective secretion by submucosal glands (SMGs), leading to persistent bacterial infection that damages airways and necessitates tissue repair. SMGs are also important niches for slow...

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書誌詳細
主要な著者: Xie, Weiliang, Fisher, John T., Lynch, Thomas J., Luo, Meihui, Evans, Turan I.A., Neff, Traci L., Zhou, Weihong, Zhang, Yulong, Ou, Yi, Bunnett, Nigel W., Russo, Andrew F., Goodheart, Michael J., Parekh, Kalpaj R., Liu, Xiaoming, Engelhardt, John F.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2011
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148720/
https://ncbi.nlm.nih.gov/pubmed/21765217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI41857
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