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Palladium‐Catalyzed Aryl Amination Reactions of 6‐Bromo‐ and 6‐Chloropurine Nucleosides

Palladium‐catalyzed C—N bond forming reactions of 6‐bromo‐ as well as 6‐chloropurine ribonucleosides and the 2′‐deoxy analogues with arylamines are described. Efficient conversions were observed with palladium(II) acetate/Xantphos/cesium carbonate, in toluene at 100 °C. Reactions of the bromonucleos...

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Detalhes bibliográficos
Main Authors: Thomson, Paul F., Lagisetty, Pallavi, Balzarini, Jan, De Clercq, Erik, Lakshman, Mahesh K.
Formato: Artigo
Idioma:Inglês
Publicado em: WILEY‐VCH Verlag 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148652/
https://ncbi.nlm.nih.gov/pubmed/21818182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adsc.200900728
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