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Epidural Administration of Liposome-Encapsulated Hydromorphone Provides Extended Analgesia in a Rodent Model of Stifle Arthritis
Liposome encapsulation of opioids by using an ammonium-sulfate–gradient loading technique significantly slows the release time of the drug. This study evaluated the duration of analgesia in a rodent model of monoarthritis after epidural administration of liposome-encapsulated hydromorphone (LE-hydro...
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Main Authors: | , , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
American Association for Laboratory Animal Science
2011
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3148635/ https://ncbi.nlm.nih.gov/pubmed/21838980 |
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