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Studies on the Biosynthesis of the Stephacidin and Notoamide Natural Products: A Stereochemical and Genetic Conundrum

The stephacidin and notoamide natural products belong to a group of prenylated indole alkaloids containing a bicyclo[2.2.2]diazaoctane core. Biosynthetically, this bicyclic core is believed to be the product of an intermolecular Diels- Alder (IMDA) cycloaddition of an achiral azadiene. Since all of...

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Autori principali: Sunderhaus, James D., Sherman, David H., Williams, Robert M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148524/
https://ncbi.nlm.nih.gov/pubmed/21818159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijch.201100016
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