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Biochemical Characterization of NotB as an FAD-Dependent Oxidase in the Biosynthesis of the Notoamide Indole Alkaloids

Notoamides produced by Aspergillus spp. bearing the bicyclo [2.2.2] diazaoctane core structure with unusual structural diversity represent a compelling system to understand the biosynthesis of fungal prenylated indole alkaloids. Herein, we report the in vitro characterization of NotB, which catalyze...

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Detalhes bibliográficos
Main Authors: Li, Shengying, Finefield, Jennifer M., Sunderhaus, James D., McAfoos, Timothy J., Williams, Robert M., Sherman, David H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3275806/
https://ncbi.nlm.nih.gov/pubmed/22188465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja2093212
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