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Cholesterol Secosterol Aldehydes Induce Amyloidogenesis and Dysfunction of Wild Type Tumor Protein p53

Epidemiologic and clinical evidence points to an increased risk of cancer when coupled with chronic inflammation. However, the molecular mechanisms that underpin this interrelationship remain largely unresolved. Herein we show that the inflammation-derived cholesterol 5,6-secosterol aldehydes, ather...

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Detaylı Bibliyografya
Asıl Yazarlar: Nieva, Jorge, Song, Byeong-Doo, Rogel, Joseph K., Kujawara, David, Altobel, Lawrence, Izharrudin, Alicia, Boldt, Grant E., Grover, Rajesh K., Wentworth, Anita D., Wentworth, Paul
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148486/
https://ncbi.nlm.nih.gov/pubmed/21802012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2011.02.018
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