Myeloid derived suppressor cell inhibition of the IFN response in tumor-bearing mice

Our group and others have determined that immune effector cells from patients with advanced cancers exhibit reduced activation of IFN signaling pathways. We hypothesized that increases in immune regulatory cells termed myeloid derived suppressor cells (MDSC) could interfere with the host immune resp...

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Autors principals: Mundy-Bosse, Bethany L., Lesinski, Gregory B., Jaime-Ramirez, Alena C., Benninger, Kristen, Khan, Mahmood, Kuppusamy, Periannan, Guenterberg, Kristan, Kondadasula, Sri Vidya, Chaudhury, Abhik Ray, La Perle, Krista M, Kreiner, Melanie, Young, Gregory, Guttridge, Denis C., Carson, William E.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148319/
https://ncbi.nlm.nih.gov/pubmed/21680779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-2670
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