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Inhibition of miR-193a expression by Max and RXRα activates K-Ras and PLAU to mediate distinct aspects of cellular transformation

MicroRNA profiling in isogenic models of cellular transformation involving either breast epithelial cells or fibroblasts reveals that expression of miR-193a is lower in transformed cells than in non-tranformed cells. The transcription factors RXRα and Max bind directly to the miR-193a promoter and i...

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Hlavní autoři: Iliopoulos, Dimitrios, Rotem, Asaf, Struhl, Kevin
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148313/
https://ncbi.nlm.nih.gov/pubmed/21670079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-0425
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