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Role of Prostaglandin Pathway and Alendronate-Based Carriers to Enhance Statin-induced Bone

OBJECTIVE: This study investigated the role of the prostaglandin (PG) pathway in locally-applied, simvastatin-induced oral bone growth. The possibility of enhancing long-term bone augmentation with an alendronate-based carrier was initiated. METHODS: Mandibles of 44 mature female rats were treated b...

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Main Authors: Lee, Yeonju, Liu, Xinming, Nawshad, Ali, Marx, David B., Wang, Dong, Reinhardt, Richard A.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148302/
https://ncbi.nlm.nih.gov/pubmed/21438610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp200045p
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