Loading...

The role of statins as potential targets for bone formation

Inhibitors of the 3-hydroxy-3-methylglutaryl coenzyme A reductase enzyme have recently been shown to stimulate bone formation in rodents both in vitro and in vivo. In bone cells, these inhibitors increase the gene expression of bone morphogenetic protein-2, which is an autocrine-paracrine factor for...

Full description

Saved in:
Bibliographic Details
Main Authors: Garrett, I Ross, Mundy, Greg R
Format: Artigo
Language:Inglês
Published: BioMed Central 2002
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC128929/
https://ncbi.nlm.nih.gov/pubmed/12106493
Tags: Add Tag
No Tags, Be the first to tag this record!