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The role of statins as potential targets for bone formation

Inhibitors of the 3-hydroxy-3-methylglutaryl coenzyme A reductase enzyme have recently been shown to stimulate bone formation in rodents both in vitro and in vivo. In bone cells, these inhibitors increase the gene expression of bone morphogenetic protein-2, which is an autocrine-paracrine factor for...

詳細記述

保存先:
書誌詳細
主要な著者: Garrett, I Ross, Mundy, Greg R
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2002
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC128929/
https://ncbi.nlm.nih.gov/pubmed/12106493
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