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Controlling nuclear JAKs and STATs for specific gene activation by IFNγ

We previously showed that gamma interferon (IFNγ) and its receptor subunit, IFNGR1, interacted with the promoter region of IFNγ-activated genes along with transcription factor STAT1α. Recent studies have suggested that activated Janus kinases pJAK2 and pJAK1 also played a role in gene activation by...

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Autors principals: Noon-Song, Ezra N., Ahmed, Chulbul M., Dabelic, Rea, Canton, Johnathan, Johnson, Howard M.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148262/
https://ncbi.nlm.nih.gov/pubmed/21689637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.06.047
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