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Aurora-A Interacts with AP-2α and Down Regulates Its Transcription Activity
Aurora-A is a serine/threonine protein kinase and plays an important role in the control of mitotic progression. Dysregulated expression of Aurora-A impairs centrosome separation and maturation, which lead to disrupted cell cycle progression and tumorigenesis. However, the molecular mechanism by whi...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3148253/ https://ncbi.nlm.nih.gov/pubmed/21829699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023110 |
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