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Dual regulation of AP-2α transcriptional activation by poly(ADP-ribose) polymerase-1
Poly(ADP-ribose) polymerase-1 (PARP-1) is a co-activator for AP-2α (activator protein 2α)-mediated transcriptional activation. In the present study, we find that the role of PARP-1 in AP-2α transcription is distinctly dualistic with opposing effects. Separate regions of PARP-1 interact with AP-2α an...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Portland Press Ltd.
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1133945/ https://ncbi.nlm.nih.gov/pubmed/15170387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040593 |
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