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Total Syntheses of Amphidinolides T1 and T4 via Catalytic, Stereoselective Reductive Macrocyclizations

Described in this work are total syntheses of amphidinolides T1 and T4 using two nickel-catalyzed reductive coupling reactions of alkynes, with an epoxide in one case (intermolecular) and with an aldehyde in another (intramolecular). The latter was used to effect a macrocyclization, form a C-C bond...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Colby, Elizabeth A., O’Brien, Karen C., Jamison, Timothy F.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2005
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148192/
https://ncbi.nlm.nih.gov/pubmed/15783211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja042733f
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