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Macrocyclization via Nickel-Catalyzed, Ester-Promoted, Epoxide–Alkyne Reductive Coupling: Total Synthesis of (−)-Gloeosporone

Macrocycles are found in important and diverse molecules such as naturally occurring peptides (e.g., cyclosporine), oligosaccharides (cyclodextrins), and polyketides (erythromycin) and synthetic compounds such as crown ethers and polyenes. The most common strategy to prepare macrocyclic lactones (ma...

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Detalhes bibliográficos
Main Authors: Trenkle, James D., Jamison, Dr. Timothy F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806845/
https://ncbi.nlm.nih.gov/pubmed/19536804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.200902079
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