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G-CSF receptor activation of the Src kinase Lyn is mediated by Gab2 recruitment of the Shp2 phosphatase

Src activation involves the coordinated regulation of positive and negative tyrosine phosphorylation sites. The mechanism whereby receptor tyrosine kinases, cytokine receptors, and integrins activate Src is not known. Here, we demonstrate that granulocyte colony-stimulating factor (G-CSF) activates...

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Bibliografski detalji
Glavni autori: Futami, Muneyoshi, Zhu, Quan-sheng, Whichard, Zakary L., Xia, Ling, Ke, Yuehai, Neel, Benjamin G., Feng, Gen-Sheng, Corey, Seth J.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148159/
https://ncbi.nlm.nih.gov/pubmed/21636860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-12-261636
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