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Comparative modeling of PON2 and analysis of its substrate binding interactions using computational methods
Paraoxonase (PON) constitutes a family of calcium-dependent mammalian enzymes comprising of PON1, PON2, and PON3. PON family shares ~60% sequence homology. These enzymes exhibit multiple activities like paraoxonase, arylesterase, and lactonase in a substrate dependent manner. Decreased PON activity...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Springer-Verlag
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3148138/ https://ncbi.nlm.nih.gov/pubmed/22319641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12177-011-9057-7 |
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