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Deconstructing Pancreas Development to Reconstruct Human Islets from Pluripotent Stem Cells

There is considerable excitement about harnessing the potential of human stem cells to replace pancreatic islets that are destroyed in type 1 diabetes mellitus. However, our current understanding of the mechanisms underlying pancreas and islet ontogeny has come largely from the powerful genetic, dev...

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Detalhes bibliográficos
Main Authors: McKnight, Kristen D., Wang, Pei, Kim, Seung K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148083/
https://ncbi.nlm.nih.gov/pubmed/20362535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2010.03.003
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