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Stress and the epigenetic landscape: a link to the pathobiology of human diseases?

Accumulating evidence points to a major role for chronic stress of cell renewal systems in the pathogenesis of important human diseases, including cancer, atherosclerosis and diabetes. Here we discuss emerging evidence that epigenetic abnormalities may make substantial contributions to these stress-...

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Detalhes bibliográficos
Main Authors: Johnstone, Sarah E., Baylin, Stephen B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148009/
https://ncbi.nlm.nih.gov/pubmed/20921961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrg2881
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