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Cancer-like epigenetic derangements of human pluripotent stem cells and their impact on applications in regeneration and repair

A growing body of work has raised concern that many human pluripotent stem cell (hPSC) lines possess tumorigenic potential following differentiation to clinically relevant lineages. In this review, we highlight recent work characterizing the spectrum of cancer-like epigenetic derangements in human e...

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Detalhes bibliográficos
Publicado no:Curr Opin Genet Dev
Main Authors: Huo, Jeffrey S., Baylin, Stephen B., Zambidis, Elias T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4262610/
https://ncbi.nlm.nih.gov/pubmed/25461449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2014.09.008
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