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The HIV-1-Specific Protein Casp8p41 Induces Death of Infected Cells through Bax/Bak
Casp8p41, a novel protein generated when HIV-1 protease cleaves caspase 8, independently causes NF-κB activation, proinflammatory cytokine production, and cell death. Here we investigate the mechanism by which Casp8p41 induces cell death. Immunogold staining and electron microscopy demonstrate that...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3147983/ https://ncbi.nlm.nih.gov/pubmed/21653671 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02515-10 |
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