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Mutation of a C-Terminal Motif Affects Kaposi's Sarcoma-Associated Herpesvirus ORF57 RNA Binding, Nuclear Trafficking, and Multimerization

The Kaposi's sarcoma-associated herpesvirus (KSHV) ORF57 protein is essential for virus lytic replication. ORF57 regulates virus gene expression at multiple levels, enhancing transcription, stability, nuclear export, and translation of viral transcripts. To enhance the nuclear export of viral i...

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Bibliografiske detaljer
Main Authors: Taylor, Adam, Jackson, Brian R., Noerenberg, Marko, Hughes, David J., Boyne, James R., Verow, Mark, Harris, Mark, Whitehouse, Adrian
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147935/
https://ncbi.nlm.nih.gov/pubmed/21593148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00138-11
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