Mutation of a C-Terminal Motif Affects Kaposi's Sarcoma-Associated Herpesvirus ORF57 RNA Binding, Nuclear Trafficking, and Multimerization

The Kaposi's sarcoma-associated herpesvirus (KSHV) ORF57 protein is essential for virus lytic replication. ORF57 regulates virus gene expression at multiple levels, enhancing transcription, stability, nuclear export, and translation of viral transcripts. To enhance the nuclear export of viral i...

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Detalhes bibliográficos
Main Authors: Taylor, Adam, Jackson, Brian R., Noerenberg, Marko, Hughes, David J., Boyne, James R., Verow, Mark, Harris, Mark, Whitehouse, Adrian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147935/
https://ncbi.nlm.nih.gov/pubmed/21593148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00138-11
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