Kaposi's sarcoma-associated herpesvirus ORF57 protein interacts with PYM to enhance translation of viral intronless mRNAs

Kaposi's sarcoma-associated herpesvirus (KSHV) expresses numerous intronless mRNAs that are unable to access splicing-dependent cellular mRNA nuclear export pathways. To circumvent this problem, KSHV encodes the open reading frame 57 (ORF57) protein, which orchestrates the formation of an expor...

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Hauptverfasser: Boyne, James R, Jackson, Brian R, Taylor, Adam, Macnab, Stuart A, Whitehouse, Adrian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885933/
https://ncbi.nlm.nih.gov/pubmed/20436455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.77
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