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Ultrasensitive Quantification of Hepatitis B Virus A1762T/G1764A Mutant by a SimpleProbe PCR Using a Wild-Type-Selective PCR Blocker and a Primer-Blocker-Probe Partial-Overlap Approach

Hepatitis B virus (HBV) carrying the A1762T/G1764A double mutation in the basal core promoter (BCP) region is associated with HBe antigen seroconversion and increased risk of liver cirrhosis and hepatocellular carcinoma (HCC). Quantification of the mutant viruses may help in predicting the risk of H...

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Detalhes bibliográficos
Main Authors: Nie, Hui, Evans, Alison A., London, W. Thomas, Block, Timothy M., Ren, Xiangdong David
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147845/
https://ncbi.nlm.nih.gov/pubmed/21562108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.02472-10
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