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Severe Alterations of Cerebellar Cortical Development after Constitutive Activation of Wnt Signaling in Granule Neuron Precursors

The Wnt/β-catenin signaling pathway plays crucial roles in early hindbrain formation, and its constitutive activity is associated with a subset of human medulloblastoma, a malignant childhood tumor of the posterior fossa. However, the precise function of Wnt/β-catenin signaling during cerebellar dev...

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Detalhes bibliográficos
Main Authors: Lorenz, Andreas, Deutschmann, Markus, Ahlfeld, Julia, Prix, Catharina, Koch, Arend, Smits, Ron, Fodde, Riccardo, Kretzschmar, Hans A., Schüller, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147790/
https://ncbi.nlm.nih.gov/pubmed/21690300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05718-11
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