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Sphingolipid Degradation by Leishmania major Is Required for Its Resistance to Acidic pH in the Mammalian Host

Leishmania parasites alternate between flagellated promastigotes in sand flies and nonflagellated amastigotes in mammals, causing a spectrum of serious diseases. To survive, they must resist the harsh conditions in phagocytes (including acidic pH, elevated temperature, and increased oxidative/nitros...

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Detalhes bibliográficos
Main Authors: Xu, Wei, Xin, Lijun, Soong, Lynn, Zhang, Kai
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147570/
https://ncbi.nlm.nih.gov/pubmed/21576322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00037-11
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