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Sphingolipid Degradation by Leishmania major Is Required for Its Resistance to Acidic pH in the Mammalian Host

Leishmania parasites alternate between flagellated promastigotes in sand flies and nonflagellated amastigotes in mammals, causing a spectrum of serious diseases. To survive, they must resist the harsh conditions in phagocytes (including acidic pH, elevated temperature, and increased oxidative/nitros...

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Bibliographische Detailangaben
Hauptverfasser: Xu, Wei, Xin, Lijun, Soong, Lynn, Zhang, Kai
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147570/
https://ncbi.nlm.nih.gov/pubmed/21576322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00037-11
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