Genetic Variation of Adenylation Domains of the Anabaenopeptin Synthesis Operon and Evolution of Substrate Promiscuity

Anabaenopeptins (AP) are bioactive cyclic hexapeptides synthesized nonribosomally in cyanobacteria. APs are characterized by several conserved motifs, including the ureido bond, N-methylation in position 5, and d-Lys in position 2. All other positions of the AP molecule are variable, resulting in nu...

Full description

Saved in:
Bibliographic Details
Main Authors: Christiansen, Guntram, Philmus, Benjamin, Hemscheidt, Thomas, Kurmayer, Rainer
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2011
Subjects:
Genetics and Molecular Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147517/
https://ncbi.nlm.nih.gov/pubmed/21622740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00360-11
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items