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Genetic Variation of Adenylation Domains of the Anabaenopeptin Synthesis Operon and Evolution of Substrate Promiscuity

Anabaenopeptins (AP) are bioactive cyclic hexapeptides synthesized nonribosomally in cyanobacteria. APs are characterized by several conserved motifs, including the ureido bond, N-methylation in position 5, and d-Lys in position 2. All other positions of the AP molecule are variable, resulting in nu...

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Detalhes bibliográficos
Main Authors: Christiansen, Guntram, Philmus, Benjamin, Hemscheidt, Thomas, Kurmayer, Rainer
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147517/
https://ncbi.nlm.nih.gov/pubmed/21622740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00360-11
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