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Increased Furfural Tolerance Due to Overexpression of NADH-Dependent Oxidoreductase FucO in Escherichia coli Strains Engineered for the Production of Ethanol and Lactate

Furfural is an important fermentation inhibitor in hemicellulose sugar syrups derived from woody biomass. The metabolism of furfural by NADPH-dependent oxidoreductases, such as YqhD (low K(m) for NADPH), is proposed to inhibit the growth and fermentation of xylose in Escherichia coli by competing wi...

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Главные авторы: Wang, X., Miller, E. N., Yomano, L. P., Zhang, X., Shanmugam, K. T., Ingram, L. O.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147458/
https://ncbi.nlm.nih.gov/pubmed/21685167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.05008-11
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