A Live-Attenuated Chimeric Porcine Circovirus Type 2 (PCV2) Vaccine Is Transmitted to Contact Pigs but Is Not Upregulated by Concurrent Infection with Porcine Parvovirus (PPV) and Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) and Is Efficacious in a PCV2b-PRRSV-PPV Challenge Model

The live chimeric porcine circovirus type 2 (PCV2) vaccine with the capsid gene of the emerging subtype 2b cloned in the genomic backbone of the nonpathogenic PCV1 is attenuated in vivo and induces protective immunity against PCV2. To further determine the safety and efficacy of this experimental va...

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Bibliographische Detailangaben
Hauptverfasser: Opriessnig, T., Shen, H. G., Pal, N., Ramamoorthy, S., Huang, Y. W., Lager, K. M., Beach, N. M., Halbur, P. G., Meng, X. J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2011
Schlagworte:
Vaccine Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147358/
https://ncbi.nlm.nih.gov/pubmed/21653745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.05057-11
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