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Monoclonal Antibodies Specific for Immunorecessive Epitopes of Glucuronoxylomannan, the Major Capsular Polysaccharide of Cryptococcus neoformans, Reduce Serotype Bias in an Immunoassay for Cryptococcal Antigen

Immunoassay for detection of glucuronoxylomannan (GXM), the major capsular polysaccharide of Cryptococcus neoformans, is an important tool for diagnosis of cryptococcosis. However, immunoassays that are based solely or in part on detection with polyclonal antibodies may show serotype bias in detecti...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Percival, Ann, Thorkildson, Peter, Kozel, Thomas R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147348/
https://ncbi.nlm.nih.gov/pubmed/21697342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.05052-11
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