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Monoclonal Antibodies Specific for Immunorecessive Epitopes of Glucuronoxylomannan, the Major Capsular Polysaccharide of Cryptococcus neoformans, Reduce Serotype Bias in an Immunoassay for Cryptococcal Antigen

Immunoassay for detection of glucuronoxylomannan (GXM), the major capsular polysaccharide of Cryptococcus neoformans, is an important tool for diagnosis of cryptococcosis. However, immunoassays that are based solely or in part on detection with polyclonal antibodies may show serotype bias in detecti...

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Библиографические подробности
Главные авторы: Percival, Ann, Thorkildson, Peter, Kozel, Thomas R.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2011
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147348/
https://ncbi.nlm.nih.gov/pubmed/21697342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.05052-11
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