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Incubation of Whole Blood at 39°C Augments Gamma Interferon (IFN-γ)-Induced Protein 10 and IFN-γ Responses to Mycobacterium tuberculosis Antigens

A rarely challenged dogma in cell-mediated immune (CMI) assays is the incubation temperature, 37°C. Fever augments proinflammatory immune responses in vivo, and the aim of this study was to explore whether incubation at fever-range temperature could increase antigen-specific biomarker responses. We...

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Detalhes bibliográficos
Main Authors: Aabye, Martine G., Ravn, Pernille, Johansen, Isik S., Eugen-Olsen, Jesper, Ruhwald, Morten
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147319/
https://ncbi.nlm.nih.gov/pubmed/21613464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00051-11
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