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IP-10, MCP-1, MCP-2, MCP-3, and IL-1RA hold promise as biomarkers for infection with M. tuberculosis in a whole blood based T-cell assay

BACKGROUND: IFN-γ responses to M. tuberculosis antigens are used as in-vitro diagnostic tests for tuberculosis infection. The tests are highly specific but sensitivity may be impaired due to immuno-suppression. The objective of this small exploratory study was to compare three novel biomarkers for i...

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Detalhes bibliográficos
Main Authors: Ruhwald, Morten, Bjerregaard-Andersen, Morten, Rabna, Paulo, Eugen-Olsen, Jesper, Ravn, Pernille
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660909/
https://ncbi.nlm.nih.gov/pubmed/19193208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-2-19
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