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Shift Reagents for IMS-IMS-MS Analysis of Complex Peptide Mixtures: Evaluation of 18-Crown-6 Ether Complexes

18-crown-6 ether (18C6) is evaluated as a shift reagent for multidimensional ion mobility spectrometry-mass spectrometry (IMS-IMS-MS) analyses of tryptic protein digests. In this approach, 18C6 is spiked into the solution-phase mixture and noncovalent peptide-crown ion complexes are formed by electr...

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Detalhes bibliográficos
Main Authors: Bohrer, Brian C., Clemmer, David E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147282/
https://ncbi.nlm.nih.gov/pubmed/21609128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac200892r
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