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Development of a high-throughput IMS-IMS-MS approach for analyzing mixtures of biomolecules

A high-throughput approach for biomolecule analysis is demonstrated for a mixture of peptides from tryptic digest of four proteins as well as a tryptic digests of human plasma. In this method a chip-based electrospray autosampler coupled to a hybrid ion mobility (IMS) mass spectrometer (MS) is utili...

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Detalhes bibliográficos
Main Authors: Kurulugama, Ruwan T., Valentine, Stephen J., Sowell, Rena A., Clemmer, David E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2626180/
https://ncbi.nlm.nih.gov/pubmed/18590839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jprot.2008.06.010
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