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Aggregation of α-Synuclein in S. cerevisiae is Associated with Defects in Endosomal Trafficking and Phospholipid Biosynthesis

Parkinson’s disease is the most common neuro-degenerative movement disorder. α-Synuclein is a small synaptic protein that has been linked to familial Parkinson’s disease (PD) and is also the primary component of Lewy bodies, the hallmark neuropathology found in the brain of sporadic and familial PD...

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Main Authors: Soper, James H., Kehm, Victoria, Burd, Christopher G., Bankaitis, Vytas A., Lee, Virginia M.-Y.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147281/
https://ncbi.nlm.nih.gov/pubmed/20890676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12031-010-9455-5
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