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α-Synuclein–induced Aggregation of Cytoplasmic Vesicles in Saccharomyces cerevisiae
Aggregated α-synuclein (α-syn) fibrils form Lewy bodies (LBs), the signature lesions of Parkinson's disease (PD) and related synucleinopathies, but the pathogenesis and neurodegenerative effects of LBs remain enigmatic. Recent studies have shown that when overexpressed in Saccharomyces cerevisi...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2262993/ https://ncbi.nlm.nih.gov/pubmed/18172022 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-08-0827 |
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