α-Synuclein–induced Aggregation of Cytoplasmic Vesicles in Saccharomyces cerevisiae

Aggregated α-synuclein (α-syn) fibrils form Lewy bodies (LBs), the signature lesions of Parkinson's disease (PD) and related synucleinopathies, but the pathogenesis and neurodegenerative effects of LBs remain enigmatic. Recent studies have shown that when overexpressed in Saccharomyces cerevisi...

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Main Authors: Soper, James H., Roy, Subhojit, Stieber, Anna, Lee, Eliza, Wilson, Robert B., Trojanowski, John Q., Burd, Christopher G., Lee, Virginia M.-Y.
Formáid: Artigo
Teanga:Inglês
Foilsithe: The American Society for Cell Biology 2008
Ábhair:
Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2262993/
https://ncbi.nlm.nih.gov/pubmed/18172022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-08-0827
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