The Glucoamylase Inhibitor Acarbose Is a Direct Activator of Phosphorylase Kinase

Phosphorylase kinase (PhK), an (αβγδ)(4) complex, stimulates energy production from glycogen in the cascade activation of glycogenolysis. Its large homologous α and β subunits regulate the activity of the catalytic γ subunit and account for 81% of PhK’s mass. Both subunits are thought to be multi-do...

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Bibliografiske detaljer
Main Authors: Nadeau, Owen W., Liu, Weiya, Boulatnikov, Igor G., Sage, Jessica M., Peters, Jennifer L., Carlson, Gerald M.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147251/
https://ncbi.nlm.nih.gov/pubmed/20604537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101006j
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