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Physicochemical changes in phosphorylase kinase associated with its activation

Phosphorylase kinase (PhK) regulates glycogenolysis through its Ca(2+)-dependent phosphorylation and activation of glycogen phosphorylase. The activity of PhK increases dramatically as the pH is raised from 6.8 to 8.2 (denoted as ↑pH), but Ca(2+) dependence is retained. Little is known about the str...

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Autori principali: Liu, Weiya, Priddy, Timothy S., Carlson, Gerald M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2590917/
https://ncbi.nlm.nih.gov/pubmed/18794211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.037895.108
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